Research finds more than 15m in US, UK, Germany and France with MASH have not been diagnosed

More than 15 million people in the US, UK, Germany and France do not know they have the most aggressive form of fatty liver disease, according to research.

Metabolic dysfunction-associated steatotic liver disease (MASLD) – the formal name for non-alcoholic fatty liver disease – occurs in people who drink no or minimal amounts of alcohol whose liver contains more than 5% fat.

About two-thirds of patients with type 2 diabetes are thought to have the condition, which is also associated with obesity, heart and circulatory disease.

Approximately 5% of adults globally have the most aggressive form of MASLD. Metabolic dysfunction-associated steatohepatitis (MASH) causes fibrosis (scarring) and can lead to cirrhosis and is linked to greater risk of cardiovascular disease, chronic kidney disease and liver cancer.

  • jet@hackertalks.com
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    2 days ago

    https://doi.org/10.1016/B978-0-12-821617-0.00010-3

    “3.2.2.3 Fatty liver – non-alcoholic fatty liver disease”

    “Clinical experience shows the treatment of carbohydrate-induced NAFLD with strict TCR is simple and rapid (3–7 days). There is no medication therapy for self-induced lifestyle disease. While treatment with insulin-sensitising drugs transiently improves NAFLD, such therapy has poor long-term value [37]. Bariatric surgery may briefly improve NAFLD, but unless CECC GLP-1 agonist medications, by suppressing gluconeogenesis, accelerates the process but may be used ancillary to but not as a substitute for TCR [38]. Abstinence from alcohol consumption accelerates fatty liver disease resolution [39].”

    I recommend the book if your really concerned about NAFLD.