This could be a good new option for those with ADHD who are currently on meds for it.

  • hypnicjerk@lemmy.world
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    19 days ago

    common blood pressure drugs are already used to treat ADHD and in my experience they’re pretty fucking bad at it compared to stimulants.

    • Avg@lemm.ee
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      5 days ago

      I’ve been on Amlodipine for over a year and it was no help at all towards my adhd, it also made my feet swell up at higher doses.

  • N0t_5ure@lemmy.world
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    19 days ago

    This is really interesting. As I was reading the article I was wondering how they were going to wring money out of it, as amlodipine is off patent. Then I got to this part:

    “While amlodipine shows promise in preclinical models, it is not currently suitable for use in ADHD in its marketed form,” Karlsson noted. “Further optimization through chemical modification is necessary to enhance CNS selectivity and ensure a favorable therapeutic index in the context of ADHD.”

    Classic big pharma. Slightly tweak an existing drug in an insignificant way so that you can get a new patent on it and charge exorbitant prices.

    • Obinice@lemmy.world
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      18 days ago

      It’ll be the same flat, cheap prescription price as all prescribed medication is though, so it doesn’t really matter what it is or how it was produced.

      It’s only countries like the USA that somehow get duped into paying wildly obese financial sums for cheap medicine. I feel for them.

    • Zenith@lemm.ee
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      18 days ago

      There’s no reason to believe those changes aren’t needed to work more effectively though, especially if it’s trying to be classified as an ADHD medication. Changing one molecule really can fundamentally change a drug, if it’s the right molecule changed the right way, it’s not inherently a cash grab, there’s not enough info here about the chemistry and its applications to make that call